NeMo Guardrails is an easy-to-use open-source toolkit from NVIDIA that empowers developers to implement guardrails for large language models (LLMs) used in conversational applications. Although LLMs hold immense potential in building interactive experiences, their inherent limitations around factual accuracy, bias and potential misuse necessitate safeguards. Guardrails offer a promising approach to ensure responsible and trustworthy LLMs. Although you have a choice when it comes to LLM guardrails, our teams have found NeMo Guardrails particularly useful because it supports programmable rules and run-time integration and can be applied to existing LLM applications without extensive code modifications.